Syllabus

Course Meeting Times

Lectures: 2 sessions / week, 1.5 hours / session

Overview

This course covers current understanding of, and modern approaches to, human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer.

Specific topics include:

• The Genetics of Simple and Complex Traits;
• Karyotypic Analysis and Positional Cloning;
• Genetic Diagnosis;
• The Roles of Oncogenes and Tumor Suppressors in Tumor Initiation, Progression and Treatment;
• The Interaction between Genetics and Environment;
• Animal Models of Human Disease and Cancer;
• Infectious Diseases including Bacterial, Viral and Eukaryotic Pathogens; and
• Disease Treatment Strategies including Drug Development and Gene Therapy.

Grading