Assigned readings are from the course text:
Watson, James D., Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick. Molecular Biology of the Gene. 5th ed. San Francisco, CA: Pearson/Benjamin Cummings, 2003. ISBN: 9780805346350 .
| Lec # | Topics | Readings |
|---|---|---|
| 1 | Replication (Replication Enzymes) | Watson, pp. 181-194. |
| 2 | Replication (Replication Fork) | Watson, pp. 195-212. |
| 3 | Replication (Prok. System) | Watson, pp. 212-221. |
| 4 | Replication (Euk. Systems) | Watson, pp. 212-221. |
| 5 | Chromatin Assembly | Watson, pp. 151-165 and 222-233. |
| 6 | DNA Mismatch Repair | Watson, chapter 9. |
| 7 | DNA Repair II | Watson, chapter 9, pp. 246-257. |
| 8 | DS Break Repair Homologous Recombination |
Watson, chapter 10, pp. 259-268. |
| 9 | Homologous Recombination Enzymes | Watson, chapter 10. |
| 10 | Meiotic Recombination | Watson, chapter 10. |
| 11 | Site-specific Recombination | Watson, chapter 10, pp. 293-310. |
| 12 | Transposition | |
| 13 | Transcription: Prok. Machinery and Promoters | |
| 14 | Transcription: Euk. Machinery and Promoters | Watson, chapter 12, pp. 347-363. |
| 15 | Transcription: Regulation I | Watson, chapter 16, pp. 483-504. |
| 16 | Transcription: Regulation II | Watson, chapter 12 and 17, pp. 363-377 and 529-551. |
| 17 | RNA Processing I | Watson, chapter 12 and 17, pp. 363-377 and 529-551. |
| 18 | RNA processing II | Watson, chapter 13. |
| 19 | RNA Processing: Regulation | Watson, chapter 13. |
| 20 | RNA Editing RNAi and miRNAs |
Watson, chapter 13, pp. 563-565. |
| 21 | Translation: Basic Machinery I | Watson, chapter 14, 16 and 17, pp. 411-454, 504-511 and 565-567. |
| 22 | Translation: Basic Machinery II | Watson, chapter 14, 16 and 17, pp. 411-454, 504-511 and 565-567. |
| 23 | Translation: Regulation I | Watson, chapter 14, 16 and 17, pp. 411-454, 504-511 and 565-567. |